Database : HANSEN
Search on : HIPERSENSIBILIDADE TARDIA/IMUNOL [Subject descriptor]
References found : 18 [refine]
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Id:13414
Author:Closs, O; Kronvall, G
Title:Experimental murine leprosy ..-
Source:s.l; s.n; 1975. 6 p. ilus, tab.
Abstract:Sera from C3H and C57BL mice infected with Mycobacterium lepraemurium (MLM) and from human leprosy patients were examined for antibodies against MLM by a crossed immunoelectrophoresis (CIE) technique. Altogether antibodies against six or seven MLM antigens were found in the mouse sera. After a small inoculum of MLM, C3H mice produced more antibodies than C57BL mice. After a large inoculum both strains produced about the same amount of antibodies but showed qualitative differences in their response patterns. A serum pool from patients with lepromatous leprosy contained antibodies against six MLM antigens; five of these were identical with the antigens against which antibodies were found in infected mice. C57BL mice that had lost their delayed-type hypersensitivity to MLM during the course of a disseminated infection showed a fairly strong antibody response to three antigens and a weak response to three others. Since almost the same spectrum of antibodies, although in lower titres, could be demonstrated in C57BL mice with intact delayed-type hypersensitivity to the bacilli, these antibodies did not seem to interfere with the expression of cell-mediated immunity.(AU).
Descriptors:MODELOS ANIMAIS DE DOENCAS
ANTIGENOS DE BACTERIAS
ANTICORPOS ANTIBACTERIAS
HIPERSENSIBILIDADE TARDIA/imunol
IMUNIDADE CELULAR
IMUNOELETROFORESE BIDIMENSIONAL
HANSENIASE/imunol
CAMUNDONGOS ENDOGÂMICOS C3H/imunol
CAMUNDONGOS ENDOGÂMICOS C57BL/imunol
MYCOBACTERIUM LEPRAEMURIUM/imunol
Limits:HUMANO
ANIMAL
FEMININO
CAMUNDONGOS
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 00024/s


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Id:13321
Author:Saha, Kunal; Mittal, Mmdan M; Ray, S. N
Title:Consequences of smallpox vaccination in leprosy patients ..-
Source:s.l; s.n; sep. 1973. 8 p. tab.
Abstract:This study illustrates the consequences of smallpox revaccination in 45 lepromatous, 28 tuberculoid, and 47 normal individuals. Results obtained with leprosy were associated with a relative anergy against the vaccinia virus, the anergy being minimal in the tuberculoid leprosy but marked in the cases with lepromatous leprosy.(AU).
Descriptors:HIPERSENSIBILIDADE TARDIA/imunol
IMUNIDADE CELULAR
IMUNOGLOBULINA A/anal
IMUNOGLOBULINA G/anal
IMUNOGLOBULINA M/anal
INJECOES INTRADERMICAS
HANSENIASE/imunol
VACINA ANTIVARIOLICA/admin
VACINACAO/ef adv
VIRUS DA VACÍNIA/imunol
FORMACAO DE ANTICORPOS
 CALOR
 HEMAGLUTINACAO
 IMUNIZACAO SECUNDARIA
 INIBICAO (PSICOLOGIA)
 MERCAPTOETANOL
 COMPLEMENTO/anal
 IMUNODIFUSAO
Limits:HUMANO
ADULTO
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 01256/s


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Id:13309
Author:Bhide, M. B; Dholam, S. B; Chatterjee, B. R
Title:Inhibition of foot pad multiplication of M. leprae in mice vaccinated with leproma derived M. leprae precursor coccoid organism and passive transfer of DTH response to normal mice through infusion of splenic cells of such vaccinated mice ..-
Source:s.l; s.n; oct. 1981. 8 p. graf.
Abstract:Inhibition of foot pad multiplication of M. leprae in mice vaccinated with leproma derived M. leprae precursor coccoid organism and passive transfer of DTH response to normal mice through infusion of splenic cells of such vaccinated mice.(AU).
Descriptors:VACINAS BACTERIANAS/imunol
HIPERSENSIBILIDADE TARDIA/imunol
IMUNIZACAO PASSIVA
MYCOBACTERIUM LEPRAE/imunol
BACO/transpl
VACINACAO
Limits:ANIMAL
CAMUNDONGOS
SUPPORT, NON-U.S. GOV'T
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 00813/s


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Id:13218
Author:Mehra, Vijay; Bloom, Barry R
Title:Induction of cell-mediated immunity to Mycobacterium leprae in guinea pigs ..-
Source:s.l; s.n; mar. 1979. 8 p. ilus, tab.
Abstract:Guinea pigs immunized with intact or disrupted armadillo-grown human Mycobacterium leprae administered in aqueous or oil vehicles were tested with various dilutions of M. leprae suspended in saline, water-soluble M. leprae extract, purified protein derivative, and a water-soluble extract of normal armadillo tissue. The results demonstrated the following. (i) Under no conditions was any skin test reactivity found to normal armadillo tissue extract. (ii) Positive sensitization to both M. leprae and its water-soluble extract was achieved by sensitizing guinea pigs with M. leprae suspended in Hanks solution or saline. Autoclaved M. leprae in Hanks solution or saline inoculated intradermally was an effective immunogen. Oil suspensions or emulsions were effective at sensitization, but appeared to be no better and, in general, slightly weaker, than simple inoculation in aqueous suspension. (iii) Living BCG failed to reveal a significant adjuvant effect on sensitization to M. leprae. However, cord factor appeared to potentiate slightly the sensitization to M. leprae in aqueous suspension. (iv) The minimum dose required for sensitization with M. leprae in aqueous suspension was 55 micrograms of purified bacilli. (v) Animals inoculated with M. leprae in saline or with M. leprae together with BCG showed positive skin test reactivity to the first skin test application made fully 1 year after the initial sensitization. The efficacy of autoclaved, irradiated M. leprae in aqueous, oil-free medium suggests a relatively safe approach to human vaccination studies.(AU).
Descriptors:HANSENIASE/imunol
MYCOBACTERIUM BOVIS/imunol
MYCOBACTERIUM LEPRAE/imunol
TESTES CUTÂNEOS
REACOES CRUZADAS
RELACAO DOSE-RESPOSTA IMUNOLOGICA
HIPERSENSIBILIDADE TARDIA/imunol
IMUNIDADE CELULAR
VACINA BCG
Limits:ANIMAL
COBAIAS
TATUS
Electronic Medium:http://www.ilsl.br
Location:BR191.1; 02201/s


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Id:12254
Author:Bourée, P; Brette, A. de; Carsalade, G. Y. de
Title:Réaction lépreuse tardive apparue 18 mois après la fin d'un traitement Late reversal leprous reaction appearing 18 months after the termination of treatment-
Source:s.l; s.n; mars 2001. 1 p. .
Descriptors:ANTIINFLAMATORIOS NAO ESTEROIDES
ANTIINFLAMATORIOS NAO ESTEROIDES
ANTIINFLAMATORIOS ESTEROIDES
ANTIINFLAMATORIOS ESTEROIDES
BIOPSIA
CLOFAZIMINA
CLOFAZIMINA
TINTURAS
SEGUIMENTOS
HIPERSENSIBILIDADE TARDIA
LEPROSTATICOS
LEPROSTATICOS
LEPROSTATICOS
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM LEPRAE
PREDNISONA
PREDNISONA
PELE
FATORES DE TEMPO
Limits:RELATO DE CASO
Location:BR191.1; 08684/s


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Id:11888
Author:Siddiqui, M. Ruby; Moreira, Andre L; Negesse, Yohannes; Taye, Genet A; Hanekom, Willem A; Haslett, Patrick A; Britton, Swen; Kaplan, Gilla
Title:Local nerve damage in leprosy does not lead to an impaired cellular immune response or decreased wound healing in the skin ..-
Source:s.l; s.n; 2002. 6 p. ilus, tab.
Descriptors:HANSENIASE
HANSENIASE
HANSENIASE
ANTIGENOS CD1
ANTIGENOS CD13
ANTIGENOS CD18
BIOPSIA
HIPERSENSIBILIDADE TARDIA
IMUNOHISTOQUIMICA
MYCOBACTERIUM LEPRAE
NEURITE
NEURITE
NEURITE
TESTE TUBERCULINICO
CICATRIZAÇAO DE FERIDAS
Location:BR191.1; 08577/s


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Id:11439
Author:Bourée, P; Brette, A. de; Carsalade, G. Y. de
Title:Réaction lépreuse tardive apparue 18 mois après la fin d'un traitement Late reveral leprous reaction appearing 18 months after the termination of treatment-
Source:s.l; s.n; 2001. 1 p. .
Descriptors:ANTIINFLAMATORIOS NAO ESTEROIDES
ANTIINFLAMATORIOS NAO ESTEROIDES
ANTIINFLAMATORIOS ESTEROIDES
ANTIINFLAMATORIOS ESTEROIDES
BIOPSIA
CLOFAZIMINA
CLOFAZIMINA
TINTURAS
SEGUIMENTOS
HIPERSENSIBILIDADE TARDIA
LEPROSTATICOS
LEPROSTATICOS
LEPROSTATICOS
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM LEPRAE
PREDNISONA
PREDNISONA
PELE
FATORES DE TEMPO
Limits:RELATO DE CASO
Location:BR191.1; 08321/s


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Id:11297
Author:Walsh, Douglas S; Villahermosa, Laarni G; Balagon, Maria V; Abalos, Rodolfo M; Fajardo Junior, Tranquilino T; Tan, Esterlina V; Cellona, Roland V; Walsh, Gerald P
Title:Cutaneous delayed-type hypersensitivity responsiveness in lepromatous and borderline lepromatous leprosy patients as determined by Multitest CMI ..-
Source:s.l; s.n; 1999. 9 p. ilus, tab, graf.
Descriptors:ADOLESCENCIA
HIPERSENSIBILIDADE TARDIA
IMUNIDADE CELULAR
HANSENIASE DIMORFA
HANSENIASE LEPROMATOSA
REPRODUTIBILIDADE DE RESULTADOS
TESTES CUTANEOS
ESTATISTICAS NAO PARAMÉTRICAS
Location:BR191.1; 07236/s


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Id:10966
Author:Naafs, Ben
Title:Viewpoint: Leprosy after the year 2000 ..-
Source:s.l; s.n; 2000. 4 p. .
Descriptors:HANSENIASE
HANSENIASE
HANSENIASE
LEPROSTATICOS
PELE
CLOFAZIMINA
QUIMIOTERAPIA COMBINADA
HIPERSENSIBILIDADE TARDIA
PREVALENCIA
SAUDE PUBLICA
RIFAMPINA
Location:BR191.1; 07425/s


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Id:9914
Author:Naafs, B
Title:Leprosy reactions: new knowledge ..-
Source:s.l; s.n; 1994. 5 p. ilus, tab.
Descriptors:HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE DIMORFA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
CITOCINAS
ERITEMA NODOSO
ERITEMA NODOSO
ERITEMA NODOSO
ERITEMA NODOSO
HIPERSENSIBILIDADE TARDIA
HIPERSENSIBILIDADE TARDIA
Location:BR191.1; 06877/s


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Id:9763
Author:Fine, Paul E. M; Sterne, Jonathan A. C; Ponnighaus, Jorg M; Rees, Richard J. W
Title:Delayed-type hypersensitivity, mycobacterial vaccines and protective immunity ..-
Source:s.l; s.n; 1994. 5 p. tab, graf.
Descriptors:HANSENIASE
HANSENIASE
HANSENIASE
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM TUBERCULOSIS
TUBERCULOSE
TUBERCULOSE
TUBERCULOSE
ANTIGENOS DE BACTÉRIAS
VACINA BCG
HIPERSENSIBILIDADE TARDIA
HIPERSENSIBILIDADE TARDIA
HIPERSENSIBILIDADE TARDIA
IMUNIDADE CELULAR
INCIDENCIA
MALAUI
PREVALENCIA
SENSIBILIDADE E ESPECIFICIDADE
TESTES CUTANEOS
Location:BR191.1; 06686/s


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Id:9759
Author:Sehgal, Virendra N; Jain, Sanjiv
Title:Chemoimmunotherapy: its relevance in contemporary context (Correspondence) ..-
Source:s.l; s.n; 1994. 2 p. .
Descriptors:HANSENIASE DIMORFA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
HANSENIASE TUBERCULOIDE
HANSENIASE TUBERCULOIDE
HANSENIASE TUBERCULOIDE
LEPROSTATICOS
HIPERSENSIBILIDADE TARDIA
IMUNIDADE CELULAR
IMUNOTERAPIA
Limits:HUMANO
Location:BR191.1; 06690/s


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Id:9754
Author:Deshpande, R. G; Khan, M. B; Navalkar, R. G
Title:Immunological evaluation of a 12-kilodalton protein of Mycobacterium tuberculosis by enzyme-linked immunosorbent assay ..-
Source:s.l; s.n; 1993. 6 p. ilus.
Descriptors:HANSENIASE
MYCOBACTERIUM LEPRAE
ANTIGENOS DE BACTÉRIAS
ANTIGENOS DE BACTÉRIAS
PROTEINAS DE BACTÉRIAS
PROTEINAS DE BACTÉRIAS
WESTERN BLOTTING
ELISA
COBAIAS
HIPERSENSIBILIDADE TARDIA
PESO MOLECULAR
PROTEINAS RECOMBINANTES
TUBERCULOSE PULMONAR
Limits:ANIMAL
HUMANO
Location:BR191.1; 06695/s


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Id:9753
Author:Deshpande, R. G; Khan, M. B; Bhat, D. A; Navalkar, R. G
Title:Superoxide dismutase activity of Mycobacterium tuberculosis isolated from tuberculosis patients and the immunoreactivity of superoxide dismutase from M. tuberculosis H37Rv ..-
Source:s.l; s.n; 1993. 7 p. ilus, tab.
Descriptors:HANSENIASE
MYCOBACTERIUM TUBERCULOSIS
MYCOBACTERIUM TUBERCULOSIS
ANTICORPOS ANTIBACTÉRIAS
WESTERN BLOTTING
ELETROFORESE EM GEL DE POLIACRILAMIDA
ELISA
HIPERSENSIBILIDADE TARDIA
SUPEROXIDO DISMUTASE
SUPEROXIDO DISMUTASE
TUBERCULOSE PULMONAR
Limits:HUMANO
Location:BR191.1; 06696/s


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Id:9324
Author:Bretscher, Peter A
Title:A strategy to improved the efficacy of vaccination against tuberculosis and leprosy ..-
Source:s.l; s.n; 1992. 4 p. .
Descriptors:VACINA BCG
VACINA BCG
VACINAS BACTERIANAS
VACINAS BACTERIANAS
SUSCETIBILIDADE A DOENÇA
SUSCETIBILIDADE A DOENÇA
RELAÇAO DOSE-RESPOSTA IMUNOLOGICA
HIPERSENSIBILIDADE TARDIA
IMUNIDADE CELULAR
LEISHMANIA TROPICA
LEISHMANIOSE CUTANEA
LEISHMANIOSE CUTANEA
HANSENIASE
HANSENIASE
HANSENIASE
CAMUNDONGOS
CAMUNDONGOS ENDOGAMICOS BALB C
CAMUNDONGOS ENDOGAMICOS BALB C
MYCOBACTERIUM BOVIS
MYCOBACTERIUM BOVIS
MYCOBACTERIUM LEPRAE
MYCOBACTERIUM TUBERCULOSIS
RATOS
TUBERCULOSE
TUBERCULOSE
TUBERCULOSE
VACINAÇAO
Limits:ANIMAL
Location:BR191.1; 06477/s


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Id:6639
Author:Schujman, Salomon
Title:Intentos de positivizar la leprominorreaccion en los casos lepromatosos: a) en los casos en actividade. b) en los casos negativizados ou "arrested" ..-
Source:s.l; s.n; 1955. 8 p. ilus.
Descriptors:HANSENIASE LEPROMATOSA
ANTIGENO DE MITSUDA
 HIPERSENSIBILIDADE TARDIA
Limits:HUMANO
ADULTO
Location:BR191.1; 05132/s


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Id:3841
Author:Mendes, Ernesto; Raphael, Açucena; Mota, Norma G. S; Mendes, Nelson F
Title:Cell-mediated immunity in leprosy and transfer of delayed hypersensivity reactions ..-
Source:s.l; s.n; 1974. 7 p. tab.
Descriptors:HANSENIASE
ANTIBIOTICOS ANTIMICOTICOS
ANTIGENOS
HIPERSENSIBILIDADE TARDIA
IMUNIDADE CELULAR
IMUNIZAÇAO
IMUNIZAÇAO PASSIVA
ANTIGENO DE MITSUDA
LINFOCITOS
NITROBENZENOS
TESTES CUTANEOS
TRICOFITINA
TESTE TUBERCULINICO
Location:BR191.1; 02681/s


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Id:3720
Author:Crawford, C. L; Evans, D. H. L; Evans, E. M
Title:Experimental allergic neurites induced by sensory nerve myelin may provide a model for nonlepromatous leprosy ..-
Source:s.l; s.n; 1974. 2 p. graf.
Descriptors:AUTO-ANTIGENOS
DOENÇAS AUTO-IMUNES
MODELOS ANIMAIS DE DOENÇAS
ADJUVANTE DE FREUND
HIPERSENSIBILIDADE TARDIA
HANSENIASE
BAINHA DE MIELINA
PROTEINAS DO TECIDO NERVOSO
NEFRITE
COELHOS
NERVO CIATICO
NERVO SURAL
Location:BR191.1; 02557/s



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